The fungus Leptosphaerulina persists in Anopheles gambiae and induces melanization
| Autor: | Joel L. Bargul, Godfrey Nattoh, Lilian Mbaisi, Jeremy K. Herren, Enock Mararo, Evan Teal, Gabriel Magoma, Hellen Butungi |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Life Cycles
Anopheles Gambiae Anopheles gambiae Disease Vectors Pathology and Laboratory Medicine Mosquitoes Medical Conditions Larvae Fungal Reproduction Medicine and Health Sciences Fungal Pathogens Multidisciplinary biology Pigmentation Fungal Diseases Anopheles Fungal genetics Eukaryota Insects Infectious Diseases Medical Microbiology Larva Medicine Pathogens Research Article Arthropoda Science Zoology Paratransgenesis Mosquito Vectors Mycology Fungus Microbiology Ascomycota parasitic diseases Genetics Animals Fungal Genetics Symbiosis Microbial Pathogens Host (biology) fungi Organisms Fungi Biology and Life Sciences Midgut biology.organism_classification Invertebrates Insect Vectors Species Interactions Leptosphaerulina Digestive System Entomology Developmental Biology |
| Zdroj: | PLoS ONE, Vol 16, Iss 2, p e0246452 (2021) Nattoh, G, Bargul, J L, Magoma, G, Mbaisi, L, Butungi, H, Mararo, E, Teal, E & Herren, J K 2021, ' The fungus Leptosphaerulina persists in Anopheles gambiae and induces melanization ', PLoS ONE, vol. 16, no. 2, e0246452 . https://doi.org/10.1371/journal.pone.0246452 PLoS ONE |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0246452 |
| Popis: | Anopheles mosquitoes are colonized by diverse microorganisms that may impact on host biology and vectorial capacity. Eukaryotic symbionts such as fungi have been isolated from Anopheles, but whether they are stably associated with mosquitoes and transmitted transstadially across mosquito life stages or to subsequent generations remains largely unexplored. Here, we show that a Leptosphaerulina sp. fungus isolated from the midgut of An. gambiae can be stably associated with An. gambiae host and that it imposes low fitness cost when re-introduced through co-feeding. This fungus is transstadially transmitted across An. gambiae developmental stages and to their progeny. It is present in field-caught larvae and adult mosquitoes at moderate levels across geographical regions. We observed that Leptosphaerulina sp. induces a distinctive melanotic phenotype across the developmental stages of mosquito. As a eukaryotic symbiont that is stably associated with An. gambiae Leptosphaerulina sp. can be explored for paratransgenesis. |
| Databáze: | OpenAIRE |
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