Histamine secretion from mast cells stimulated with somatostatin
Autor: | T. A. Kassessinoff, Frederick L. Pearce |
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Rok vydání: | 1988 |
Předmět: |
medicine.medical_specialty
Polymers Histamine secretion Guinea Pigs Immunology In Vitro Techniques Biology Toxicology Histamine Release Cell membrane Mice chemistry.chemical_compound Cricetinae Internal medicine Polyamines medicine Animals Pharmacology (medical) Mast Cells Histamine H4 receptor Receptor Pharmacology Rats Inbred Strains Mast cell Polyelectrolytes Rats Somatostatin Endocrinology medicine.anatomical_structure chemistry biology.protein Antibody Histamine |
Zdroj: | Agents and Actions. 23:211-213 |
ISSN: | 1420-908X 0065-4299 |
DOI: | 10.1007/bf02142543 |
Popis: | Histamine release from isolated mast cells stimulated with somatostatin resembled that induced by other basic agents. The process was rapid, independent of added calcium or phospholipids, non-cytotoxic, species and tissue specific, not mediated through cell-fixed antibodies or glucoreceptors, and inhibited by antagonists of the polyamine receptor. Somatostatin and other polycations may then act through a common receptor or binding site on the mast cell membrane. |
Databáze: | OpenAIRE |
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