The impact of critical illness on the expiratory muscles and the diaphragm assessed by ultrasound in mechanical ventilated children
| Autor: | IJland, Marloes M., Lemson, Joris, van der Hoeven, Johannes G., Heunks, Leo M. A. |
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| Přispěvatelé: | Intensive care medicine, ACS - Pulmonary hypertension & thrombosis |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Vascular damage Radboud Institute for Health Sciences [Radboudumc 16] Diaphragm Critical Care and Intensive Care Medicine All institutes and research themes of the Radboud University Medical Center Mechanical ventilation Atrophy Internal medicine Anesthesiology Ultrasound medicine Respiratory muscle Respiratory system Children Pediatric intensive care unit business.industry Research lcsh:Medical emergencies. Critical care. Intensive care. First aid lcsh:RC86-88.9 medicine.disease Diaphragm (structural system) lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4] Cardiology Expiratory muscles business |
| Zdroj: | Annals of Intensive Care, 10(1):115. Springer-Verlag GmbH and Co. KG IJland, M M, Lemson, J, van der Hoeven, J G & Heunks, L M A 2020, ' The impact of critical illness on the expiratory muscles and the diaphragm assessed by ultrasound in mechanical ventilated children ', Annals of Intensive Care, vol. 10, no. 1, 115 . https://doi.org/10.1186/s13613-020-00731-2 Annals of Intensive Care, Vol 10, Iss 1, Pp 1-11 (2020) Annals of Intensive Care Annals of Intensive Care, 10, 1 Annals of Intensive Care, 10 |
| ISSN: | 2110-5820 |
| DOI: | 10.1186/s13613-020-00731-2 |
| Popis: | Background Critical illness has detrimental effects on the diaphragm, but the impact of critical illness on other major muscles of the respiratory pump has been largely neglected. This study aimed to determine the impact of critical illness on the most important muscles of the respiratory muscle pump, especially on the expiratory muscles in children during mechanical ventilation. In addition, the correlation between changes in thickness of the expiratory muscles and the diaphragm was assessed. Methods This longitudinal observational cohort study performed at a tertiary pediatric intensive care unit included 34 mechanical ventilated children (> 1 month– Results Over the first 4 days, both diaphragm and expiratory muscles thickness decreased (> 10%) in 44% of the children. Diaphragm and expiratory muscle thickness increased (> 10%) in 26% and 20% of the children, respectively. No correlation was found between contractile activity of the muscles and the development of atrophy. Furthermore, no correlation was found between changes in thickness of the diaphragm and the expiratory muscles (P = 0.537). Decrease in expiratory muscle thickness was significantly higher in patients failing extubation compared to successful extubation (− 34% vs − 4%, P = 0.014). Conclusions Changes in diaphragm and expiratory muscles thickness develop rapidly after the initiation of mechanical ventilation. Changes in thickness of the diaphragm and expiratory muscles were not significantly correlated. These data provide a unique insight in the effects of critical illness on the respiratory muscle pump in children. |
| Databáze: | OpenAIRE |
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