Ebola Virus Infection Associated with Transmission from Survivors

Autor: Oliver Morgan, Mamadou Harouna Djingarey, Devin Perkins, Hugh Henry W Green, Barbara J. Marston, Schabbethai S. Senesie, A.H. Shah, Esther L Hamblion, Saskia Den Boon, Sakoba Keita, Alex Gasasira, Christopher Dye, Ian Crozier, Nuha Mahmoud, Moumié Barry, Tolbert Nyenswah, Kara N. Durski, Margaret Lamunu, Amara Jambai
Rok vydání: 2019
Předmět:
Male
Epidemiology
Expedited
viruses
lcsh:Medicine
Disease
medicine.disease_cause
Disease Outbreaks
West africa
law.invention
viral persistence
0302 clinical medicine
law
Medicine
Public Health Surveillance
030212 general & internal medicine
response
survivors
Middle Aged
Ebolavirus
Africa
Western
Infectious Diseases
Transmission (mechanics)
Synopsis
surveillance
Female
Ebola virus infection
Adult
Microbiology (medical)
Sexual transmission
Adolescent
030231 tropical medicine
Ebola virus disease
Sierra Leone
lcsh:Infectious and parasitic diseases
Young Adult
03 medical and health sciences
Strength of evidence
West Africa
Humans
lcsh:RC109-216
Ebola virus
business.industry
lcsh:R
Outbreak
Hemorrhagic Fever
Ebola
Liberia
Virology
sexual transmission
Ebola Virus Infection Associated with Transmission from Survivors
Guinea
business
Zdroj: Emerging Infectious Diseases, Vol 25, Iss 2, Pp 240-246 (2019)
Emerging Infectious Diseases
ISSN: 1080-6059
1080-6040
DOI: 10.3201/eid2502.181011
Popis: Ebola virus (EBOV) can persist in immunologically protected body sites in survivors of Ebola virus disease, creating the potential to initiate new chains of transmission. From the outbreak in West Africa during 2014-2016, we identified 13 possible events of viral persistence-derived transmission of EBOV (VPDTe) and applied predefined criteria to classify transmission events based on the strength of evidence for VPDTe and source and route of transmission. For 8 events, a recipient case was identified; possible source cases were identified for 5 of these 8. For 5 events, a recipient case or chain of transmission could not be confidently determined. Five events met our criteria for sexual transmission (male-to-female). One VPDTe event led to at least 4 generations of cases; transmission was limited after the other events. VPDTe has increased the importance of Ebola survivor services and sustained surveillance and response capacity in regions with previously widespread transmission.
Databáze: OpenAIRE
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