A clinical study to measure anti-erosion properties of a stabilized stannous fluoride dentifrice relative to a sodium fluoride/triclosan dentifrice
Autor: | Joon Seong, Nicola Hellin, Nicola X West, Tao He, H Eynon, Matthew L Barker |
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Rok vydání: | 2015 |
Předmět: |
Adult
Male Dentistry 02 engineering and technology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Double-Blind Method Sodium fluoride Dentifrice Medicine Humans Dentistry (miscellaneous) Fluorides Topical Tooth Erosion Dentifrices Aged Orange juice Cross-Over Studies Enamel paint business.industry 030206 dentistry Middle Aged 021001 nanoscience & nanotechnology Tooth enamel Triclosan medicine.anatomical_structure chemistry visual_art visual_art.visual_art_medium Tin Fluorides Sodium Fluoride Female 0210 nano-technology business Fluoride Sodium fluoride + triclosan |
Zdroj: | International journal of dental hygiene. 15(2) |
ISSN: | 1601-5037 |
Popis: | Objective To compare the enamel protection efficacy of a stabilized stannous fluoride (SnF2) dentifrice to a sodium fluoride (NaF)/triclosan dentifrice following acidic erosive challenge. Methods In this in situ, randomized, controlled, double-blind, two-treatment, four-period crossover clinical trial, subjects wore an appliance fitted with human enamel samples 6 h day−1 during each 15-day treatment period. Twice each treatment day they swished with their assigned dentifrice slurry: 0.454% SnF2/0.077% NaF or 0.32% NaF/0.3% triclosan. After each treatment and two other times daily, subjects swished with 250 ml of orange juice over a 10-min period (acidic erosive challenge). Enamel samples were measured for tooth surface loss using contact profilometry at baseline and days 10 and 15. Results Thirty-six subjects (mean age 44.8 years, range 23–65 years) were randomized to treatment; 33 subjects completed the final study visit. There were no statistically significant baseline differences (P > 0.44) in the specimen surfaces of the two dentifrice treatment groups via profilometry. At day 10, the SnF2 dentifrice provided a statistically significant (P |
Databáze: | OpenAIRE |
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