An Exceptional Vulvar Tumor
| Autor: | Floris H. Groenendijk, Mark-David Levin, Leonard A. Noorduyn, Karishma P. Ramlakhan, Sjarlot G. Kooi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty Myeloid Chronic myelomonocytic leukemia Blastoid Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine medicine Myeloid sarcoma Humans Leukocytosis Sarcoma Myeloid Aged Vulvar Neoplasms biology business.industry Obstetrics and Gynecology Labia majora medicine.disease biology.organism_classification 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis Female Sarcoma Bone marrow medicine.symptom business |
| Zdroj: | International Journal of Gynecological Pathology. 39:111-114 |
| ISSN: | 0277-1691 |
| DOI: | 10.1097/pgp.0000000000000595 |
| Popis: | Vulvar malignancies are rare and have diverse origins and presentations. The majority of these tumors are squamous cell carcinoma. An ulcerating vulvar tumor was found in a 74-yr-old woman presenting with fatigue and leukocytosis. Tumor biopsy revealed infiltration of blastoid cells from myeloid origin. Through bone marrow aspiration chronic myelomonocytic leukemia was diagnosed, of which the vulvar tumor was a rare extramedullary disease manifestation termed myeloid sarcoma. Limited palliative treatment was instated with a focus on the patient's quality of life. Myeloid sarcoma (chloroma; granulocytic sarcoma) is a mass of myeloblasts occurring in cases of myeloid disease. Manifestations in most organ systems have been described. Presentation in gynecologic areas is reported in a few case reports, to which we now add our experience. |
| Databáze: | OpenAIRE |
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