Qingfeijianpi therapy for persistent allergic rhinitis: A randomized, positive-controlled clinical trial
| Autor: | Hai-Hong Lian, Nan Zhi, Jing Qu, Xiang-Dong Wang, Chang Liu |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Treatment outcome MEDLINE Severity of Illness Index law.invention Loratadina Treatment and control groups 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Internal medicine Severity of illness Anti-Allergic Agents medicine Humans business.industry General Medicine Loratadine Middle Aged Rhinitis Allergic Clinical trial 030104 developmental biology Treatment Outcome 030228 respiratory system Female business Drugs Chinese Herbal |
| Zdroj: | Medicine. 97(23) |
| ISSN: | 1536-5964 |
| Popis: | This study aims to investigate the effectiveness and safety of Qingfeijianpi therapy for persistent allergic rhinitis (AR).A total of 101 patients with persistent AR were included into the study. These patients were randomly divided into 2 groups: treatment group, in which patients were given Qingfeijianpi decoction (1 dose/day for 4 weeks); control group, in which patients were given an oral dose of loratadine (tablet, 10 mg/time, once per day for 4 weeks). A total of 96 patients completed the 16-week course of treatment. The nasal symptom and traditional Chinese medicine syndrome were scored to evaluate symptom improvement, and the Rhinoconjunctivitis Quality of Life Questionnaire was used to assess the quality of life of patients. Furthermore, the 4-week clinical treatment effect and 16-week follow up were evaluated.After the 4-week treatment, the mean difference in symptom score in the treatment group was similar to that in the control group. However, during the follow-up, the decrease in symptom score was better with the Qingfeijianpi therapy than with loratadine.Compared to loratadine, the Qingfeijianpi decoction exhibited a significant benefit in symptom improvement of persistent AR. |
| Databáze: | OpenAIRE |
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