| Autor: |
Blake, Maja K., O���Connell, Patrick, Pepelyayeva, Yuliya, Godbehere, Sarah, Aldhamen, Yasser A., Amalfitano, Andrea |
| Rok vydání: |
2022 |
| DOI: |
10.6084/m9.figshare.19311770.v1 |
| Popis: |
Additional file 2. Supplemental Figure 2: Increased cytokine and chemokine production from ERAP1-/- macrophages following NLRP3 inflammasome activation. Heat map depicting the top 12 upregulated and downregulated cytokines by ERAP1. Bone marrow-derived macrophages (BMDMs) from C57 WT and ERAP1-/- mice were primed with LPS (20 ng/mL) for 12 hours. Cells were then stimulated with nigericin (10 ug/mL) for an additional 20 hours. Supernatants were collected and analyzed used in a 23-plex multiplex assay using Bioplex. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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