SUCCESSFUL TREATMENT OF KASABACH-MERRITT SYNDROME WITH VINCRISTINE AND DIAGNOSIS OF THE HEMANGIOMA USING THREE-DIMENSIONAL IMAGING
| Autor: | Teruyuki Kajiume, Keiichi Hara, Norioki Ohno, Tomoaki Yoshida, Masao Kobayashi, Hiroshi Kawaguchi |
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| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Vincristine medicine.drug_class Ecchymosis Kasabach–Merritt syndrome Guanidines Hemangioma Coagulopathy Humans Medicine business.industry Anti-Inflammatory Agents Non-Steroidal Infant Syndrome Hematology Disseminated Intravascular Coagulation medicine.disease Antineoplastic Agents Phytogenic Magnetic Resonance Imaging Thrombocytopenia Benzamidines Surgery body regions Three dimensional imaging Oncology Pediatrics Perinatology and Child Health Corticosteroid medicine.symptom Tomography X-Ray Computed business medicine.drug Congenital disorder |
| Zdroj: | Pediatric Hematology and Oncology. 26:375-380 |
| ISSN: | 1521-0669 0888-0018 |
| Popis: | Kasabach-Merritt syndrome is a life-threatening congenital disorder characterized by an enlarging hemangioma, thrombocytopenia, and consumption coagulopathy. We report the case of a one-month male infant who presented with a large cutaneous tumor in his right axilla with ecchymosis, thrombocytopenia, and chronic consumption coagulopathy. Three-dimensional computed tomography was useful for accurate diagnosis of the cutaneous tumor and for determining the precise vascular constitution of the hemangioma, suggesting the efficacy of this method for diagnosing Kasabach-Merritt syndrome. Although administration of a corticosteroid was not effective, additional administration of vincristine resulted in the reversal of thrombocytopenia and coagulopathy with reduction of the hemangioma. |
| Databáze: | OpenAIRE |
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