Differentiation of focal autoimmune pancreatitis from pancreatic ductal adenocarcinoma
| Autor: | Pardeep Mittal, Frank H. Miller, Joon Soo Shin, Nancy A. Hammond, Kunal Kothari, Camila Lopes Vendrami |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Pathology CA-19-9 Antigen Autoimmune Pancreatitis Urology 030218 nuclear medicine & medical imaging Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Adrenal Cortex Hormones Internal medicine Pancreatic cancer medicine Humans Radiology Nuclear Medicine and imaging Autoimmune pancreatitis Radiological and Ultrasound Technology business.industry Gastroenterology Cancer Hepatology Jaundice medicine.disease Pancreatic Neoplasms medicine.anatomical_structure Immunoglobulin G 030220 oncology & carcinogenesis Adenocarcinoma Pancreatitis medicine.symptom Pancreas business Biomarkers Carcinoma Pancreatic Ductal |
| Zdroj: | Abdominal Radiology. 45:1371-1386 |
| ISSN: | 2366-0058 2366-004X |
| DOI: | 10.1007/s00261-019-02210-0 |
| Popis: | Autoimmune pancreatitis (AIP) is an inflammatory process of the pancreas that occurs most commonly in elderly males and clinically can mimic pancreatic adenocarcinoma and present with jaundice, weight loss, and abdominal pain. Mass-forming lesions in the pancreas are seen in the focal form of AIP and both clinical and imaging findings can overlap those of pancreatic cancer. The accurate distinction of AIP from pancreatic cancer is of utmost importance as it means avoiding unnecessary surgery in AIP cases or inaccurate steroid treatment in patients with pancreatic cancer. Imaging concomitantly with serological examinations (IgG4 and Ca 19-9) plays an important role in the distinction between these entities. Characteristic extra-pancreatic manifestations as well as favorable good response to treatment with steroids are characteristic of AIP. This paper will review current diagnostic parameters useful in differentiating between focal AIP and pancreatic adenocarcinoma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink