Estrogenic activity of the bis (γ -methylthiobutyryl) ester of diethylstilbestrol
| Autor: | Ernest G. Jaworski, N. DeGubareff, Frank Hertelendy |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
endocrine system
medicine.medical_specialty animal structures Diethylstilbestrol Stimulation Oviducts Sulfides General Biochemistry Genetics and Molecular Biology Muscle hypertrophy Mice Internal medicine medicine Animals Bioassay General Pharmacology Toxicology and Pharmaceutics Young female urogenital system Chemistry Body Weight Uterus Broiler Esters Estrogens Hypertrophy Organ Size General Medicine Lipids Butyrates Endocrinology Oviduct Biological Assay Female Chemical and Drug Induced Liver Injury Chickens hormones hormone substitutes and hormone antagonists medicine.drug Hormone |
| Zdroj: | Life Sciences. 10:851-856 |
| ISSN: | 0024-3205 |
| DOI: | 10.1016/0024-3205(71)90156-1 |
| Popis: | The bis (γ -methylthiobutyryl) ester of diethylstilbestrol possessed higher estrogenic activity than diethylstilbestrol based on mouse uterine bioassays. A similar comparison of these hormones in young female broiler chicks resulted in approximately the same stimulation of oviduct development, but the ester did not cause hypertrophy of the liver nor did it elevate plasma lipids to the degree found with diethylstilbestrol. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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