Tobacco smoking and cannabis use in a longitudinal birth cohort: Evidence of reciprocal causal relationships
| Autor: | Joseph M. Boden, David M. Fergusson, Silvana De Pirro, Aldo Badiani, Gordon Thomas Harold, L. John Horwood |
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| Rok vydání: | 2015 |
| Předmět: |
cannabis
Longitudinal study medicine.medical_specialty longitudinal study structural equation modelling tobacco adolescent adult alcohol-related disorders anxiety disorders comorbidity depressive disorder major female humans life change events longitudinal studies male marijuana smoking new zealand peer group smoking young adult models statistical psychiatry and mental health toxicology pharmacology pharmacology (medical) medicine (all) Alcohol use disorder major Toxicology Logistic regression models depressive disorder medicine Pharmacology (medical) Psychiatry Pharmacology Depressive Disorder Major Models Statistical biology Confounding medicine.disease biology.organism_classification Substance abuse Psychiatry and Mental health Cohort Cannabis Psychology statistical Anxiety disorder |
| Zdroj: | Drug and Alcohol Dependence. 150:69-76 |
| ISSN: | 0376-8716 |
| Popis: | BACKGROUND There is evidence of associations between tobacco and cannabis use that are consistent with both a classical stepping-stone scenario that posits the transition from tobacco use to cannabis use ('gateway' effect of tobacco) and with the reverse process leading from cannabis use to tobacco abuse ('reverse gateway' effect of cannabis). The evidence of direct causal relationships between the two disorders is still missing. METHODS We analysed data from the Christchurch Health and Development Study (CHDS) longitudinal birth cohort using advanced statistical modelling to control for fixed sources of confounding and to explore causal pathways. The data were analysed using both: (a) conditional fixed effects logistic regression modelling; and (b) a systematic structural equation modelling approach previously developed to investigate psychiatric co-morbidities in the same cohort. RESULTS We found significant (p |
| Databáze: | OpenAIRE |
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