Vitamin D3 deficiency is associated with more severe insulin resistance and metformin use in patients with type 2 diabetes
| Autor: | Nazarii Kobyliak, Mahmoud Aludwan, Rinaldo Pellicano, Dmytro Kyriienko, Ludovico Abenavoli, Sharmila Fagoonee, Iuliia Komisarenko |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Vitamin
Adult Male medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Type 2 diabetes Glycemic Control Body Mass Index 03 medical and health sciences chemistry.chemical_compound Young Adult 0302 clinical medicine Endocrinology Insulin resistance Diabetes mellitus Internal medicine Internal Medicine medicine Humans Hypoglycemic Agents Obesity Aged Cholecalciferol C-Peptide business.industry Middle Aged medicine.disease Vitamin D Deficiency Metformin Cross-Sectional Studies chemistry type 2 Diabetes Mellitus Type 2 030220 oncology & carcinogenesis Ergocalciferols Female Hemoglobin Insulin Resistance business Body mass index Homeostasis medicine.drug |
| Zdroj: | Minerva endocrinologica (Testo stamp.) 45 (2020): 172–180. doi:10.23736/S0391-1977.20.03161-2 info:cnr-pdr/source/autori:Aludwan, Mahmoud; Kobyliak, Nazarii; Abenavoli, Ludovico; Kyriienko, Dmytro; Fagoonee, Sharmila; Pellicano, Rinaldo; Komisarenko, Iuliia/titolo:Vitamin D3 deficiency is associated with more severe insulin resistance and metformin use in patients with type 2 diabetes/doi:10.23736%2FS0391-1977.20.03161-2/rivista:Minerva endocrinologica (Testo stamp.)/anno:2020/pagina_da:172/pagina_a:180/intervallo_pagine:172–180/volume:45 |
| ISSN: | 1827-1634 |
| DOI: | 10.23736/S0391-1977.20.03161-2 |
| Popis: | Background: Vitamin D3 (vit. D3) deficiency is considered as one of the main factors involved in the development of type 2 diabetes (T2D). We assessed insulin resistance (IR), ?-cell functional activity and metabolic profile according to 25(OH) vit. D3 status in patients with T2D. Methods: The study included 109 patients with T2D, divided in 3 groups: group 1 (N.=11) with normal levels of vit. D3 (>30 ng/mL); group 2 (N.=38) with vit. D3 insufficiency (21-29 ng/mL); and group 3 (N.=60) with vit. D3 deficiency ( |
| Databáze: | OpenAIRE |
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