A clinical MRI investigation of the relationship between kidney volume measurements and renal function in patients with renovascular disease
| Autor: | R S Nicholas, T B McLeay, Stephen J. Gandy, John Graeme Houston, K Armoogum |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Gauche effect Renal Artery Obstruction Renal function Kidney Volume Kidney Kidney Function Tests Magnetic resonance angiography medicine.artery Medicine Humans Radiology Nuclear Medicine and imaging Renal artery Aged Aged 80 and over Reproducibility Analysis of Variance medicine.diagnostic_test urogenital system business.industry General Medicine Organ Size Middle Aged medicine.anatomical_structure Hypertension Renovascular Female Radiology business Nuclear medicine Magnetic Resonance Angiography Glomerular Filtration Rate |
| Zdroj: | Europe PubMed Central |
| ISSN: | 1748-880X |
| Popis: | Recent improvements in MR image acquisition and post-processing techniques have allowed quantitative kidney volume measurements to be derived from patient studies. These morphological indices can provide "snapshot" assessments that may be related to kidney function. The study objective was to measure cortical and total kidney volumes in patients with renovascular disease (RVD) using contrast-enhanced MR angiography (CE-MRA) in order to assess the reproducibility of the technique and to investigate associations between volumes and renal function as measured by glomerular filtration rate (GFR) calculations. 50 patients with RVD were scanned using CE-MRA. Kidney lengths, volumes and renal artery stenoses (RAS) were evaluated, and GFR was calculated using clinical formulae and nuclear medicine isotope renography. Mean MRI kidney lengths were 10.3+/-0.2 cm, and mean MRI volumes were 74.9+/-3.6 cm3 (cortical) and 128.5+/-5.3 cm3 (total). Kidneys supplied by moderately stenosed arteries had enlarged lengths and volumes, whilst those supplied by severely stenosed arteries had significantly smaller lengths (p |
| Databáze: | OpenAIRE |
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