Effectiveness and Safety of Camylofin in Augmentation of Labor: A Systematic Review and Meta-Analysis
| Autor: | Hemant Mehta, Ameya Purandare, Nandita P. Palshetkar, Rohan Palshetkar |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
030219 obstetrics & reproductive medicine
Nausea business.industry Obstetrics and Gynecology Camylofin Confidence interval 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Vaginal tear chemistry Meta-analysis Anesthesia medicine Vomiting 030212 general & internal medicine Cervical dilatation medicine.symptom Drotaverine business Systematic Reviews/Meta-analysis medicine.drug |
| Zdroj: | J Obstet Gynaecol India |
| ISSN: | 0975-6434 0971-9202 |
| Popis: | This systematic review and meta-analysis assessed the effectiveness and safety of camylofin compared with other antispasmodics (drotaverine, hyoscine, valethamate, phloroglucinol, and meperidine) in labor augmentation. A systematic literature search until March 27, 2018, was performed, and data on the cervical dilatation rate (CDR) and duration of stages of labor reported in 39 eligible articles were analyzed using a random-effects model. CDR was significantly higher (0.38 cm/h, 95% confidence interval (CI) 0.10 to 0.67, p = 0.007), and the duration of the first stage of labor was significantly shorter (− 41.21 minutes, 95% CI, − 77.19 to − 5.22, p = 0.02) in women receiving camylofin than those receiving other antispasmodics for labor augmentation. CDR was significantly higher with camylofin compared with valethamate (0.6 cm/h, 95% CI 0.4 to 0.9, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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