A Convenient Protecting Group for Uridine Ureido Nitrogen: (4,4′-Bisfluorophenyl)methoxymethyl Group

Autor:	Katsuhiko Mitachi, David Mingle, Michio Kurosu
Rok vydání:	2021
Předmět:	chemistry.chemical_compound Chemical transformation Group (periodic table) Chemistry Organic Chemistry chemistry.chemical_element Protecting group Medicinal chemistry Nitrogen Article Catalysis Relative stability Uridine
Zdroj:	Synthesis (Stuttg)
ISSN:	1437-210X 0039-7881
DOI:	10.1055/a-1464-2473
Popis:	(4,4′-Bisfluorophenyl)methoxymethyl (BFPM) group of uridine ureido nitrogen shows good relative stability in a variety of chemical transformation reactions for uridine. The BFPM group can be cleaved by 2% of TFA in CH2Cl2 without affecting the Boc group.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715df8e2938bfc1d1e58a431b1ab78db https://doi.org/10.1055/a-1464-2473 Zobrazit plný text záznamu