A Systematic Review and Meta-Analysis of Methods Used to Reduce Infectious Complications Following Transrectal Prostate Biopsy
| Autor: | Seyed Behzad Jazayeri, Gretchen M Kuntz, Karthik Tanneru, K.C. Balaji, Shahriar Koochekpour, Hariharan Palayapalayam Ganapathi, Mark Bandyk, Soroush T. Bazargani, Sabine Nguyen, Jatinder Kumar, Muhammad Umar Alam, Robert Marino, Joseph Costa |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty business.industry medicine.drug_class Biopsy Urology Antibiotics Prostate Rectum 030232 urology & nephrology MEDLINE Bacterial Infections Anti-Bacterial Agents 03 medical and health sciences Postoperative Complications 0302 clinical medicine 030220 oncology & carcinogenesis Meta-analysis Internal medicine medicine Humans business Transrectal Prostate Biopsy |
| Zdroj: | Urology. 144:21-27 |
| ISSN: | 0090-4295 |
| Popis: | We reviewed and analyzed the most effective methods to reduce infectious complications (IC) after transrectal prostate biopsy (TRPB). We included only prospective randomized-controlled trials in the analysis. The analysis neither demonstrated any superiority of fluoroquinolones over other antibiotic classes nor of targeted antibiotics over empiric regimens in men undergoing TRPB. However, longer course antibiotics (3 days or more) compared to single dose or day regimens, combination of fluoroquinolones with aminoglycosides compared to fluoroquinolones alone and povidone-iodine rectal cleansing compared to control significantly reduced IC following TRPB. A combination of addition of aminoglycosides to oral antibiotics for 3 days along with povidone-iodine rectal cleansing may be an optimum strategy to minimize the risk of IC after TRPB. |
| Databáze: | OpenAIRE |
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