Association between enteral nutrition support and neurological outcome in patients with acute intracranial haemorrhage: A retrospective cohort study
| Autor: | Yingting Xu, Xuandong Jiang, Weizhe Ru, Xuping Cheng, Yanfei Shen, Yongxia Hu, Kailei Du, Weimin Zhang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty lcsh:Medicine Single Center Article Cohort Studies 03 medical and health sciences 0302 clinical medicine Enteral Nutrition Internal medicine medicine Humans Nutrition disorders 030212 general & internal medicine lcsh:Science Propensity Score Retrospective Studies 030109 nutrition & dietetics Multidisciplinary business.industry lcsh:R Glasgow Coma Scale Retrospective cohort study Odds ratio Prognosis Confidence interval Parenteral nutrition Treatment Outcome Quartile Propensity score matching lcsh:Q Female Nervous System Diseases business Energy Intake Intracranial Hemorrhages Neurological disorders |
| Zdroj: | Scientific Reports Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019) |
| ISSN: | 2045-2322 |
| Popis: | Association between the amount of enteral nutrition (EN) caloric intake and Glasgow coma scale scores at discharge (GCSdis) in intracranial haemorrhage (ICH) was retrospectively investigated in 230 patients in a single center from 2015 and 2017. GCSdis was used as a dichotomous outcome (≤8 or >8: 56/230 vs. 174/230) and its association with the amount of EN caloric intake within 48 hours was analysed in four logistic models. Model 1 used EN as a continuous variable and showed association with favourable GCSdis (odds ratio [OR], 1.04; 95% confidence interval [CI], 1.01–1.08). Models 2 and 3 categorized EN into two (≤25 and >25 kcal/kg/48 hrs) and three caloric intake levels (≤10, 10~25, and >25 kcal/kg/48 hrs) respectively, and compared them with the lowest level; highest EN level associated with favourable GCSdis in both model 2 (OR, 2.77; 95%CI, 1.25–6.13) and 3 (OR, 4.68; 95%CI, 1.61–13.61). Model 4 transformed EN into four quartiles (Q1-Q4). Compared to Q1, OR increased stepwise from Q2 (OR 1.80, 95%CI 0.59–5.44) to Q4 (OR 4.71, 95%CI 1.49–14.80). Propensity score matching analysis of 69 matched pairs demonstrated consistent findings. In the early stage of ICH, increased EN was associated with favourable GCSdis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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