Comparison of Spatial Summation Properties of Neurons in Macaque V1 and V2
| Autor: | Jonathan B. Levitt, Alessandra Angelucci, Jennifer M. Ichida, S. Shushruth |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Visual perception
Physiology Surround suppression Models Neurological Action Potentials Grating Summation Macaque 03 medical and health sciences 0302 clinical medicine Optics biology.animal medicine Animals Cluster Analysis Visual Cortex 030304 developmental biology Neurons Physics 0303 health sciences Communication biology business.industry General Neuroscience Articles Macaca fascicularis Visual cortex medicine.anatomical_structure Modulation Receptive field Linear Models Visual Perception business Microelectrodes Photic Stimulation 030217 neurology & neurosurgery |
| Zdroj: | Journal of Neurophysiology |
| ISSN: | 1522-1598 0022-3077 |
| DOI: | 10.1152/jn.00512.2009 |
| Popis: | In visual cortex, responses to stimulation of the receptive field (RF) are modulated by simultaneous stimulation of the RF surround. The mechanisms for surround modulation remain unidentified. We previously proposed that in the primary visual cortex (V1), near surround modulation is mediated by geniculocortical and horizontal connections and far surround modulation by interareal feedback connections. To understand spatial integration in the secondary visual cortex (V2) and its underlying circuitry, we have characterized spatial summation in different V2 layers and stripe compartments and compared it to that in V1. We used grating stimuli in circular and annular apertures of different sizes to estimate the extent and sensitivity of RF and surround components in V1 and V2. V2 RFs and surrounds were twice as large as those in V1. As in V1, V2 RFs doubled in size when measured at low contrast. In both V1 and V2, surrounds were about fivefold the size of the RF and the far surround could exceed 12.5 degrees in radius, averaging 5.5 degrees in V1 and 9.2 degrees in V2. The strength of surround suppression was similar in both areas. Thus although differing in spatial scale, the interactions among RF components are similar in V1 and V2, suggesting similar underlying mechanisms. As in V1, the extent of V2 horizontal connections matches that of the RF center, but is much smaller than the largest far surrounds, which likely derive from interareal feedback. In V2, we found no laminar or stripe differences in size and magnitude of surround suppression, suggesting conservation across stripes of the basic circuit for surround modulation. |
| Databáze: | OpenAIRE |
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