Design of a compartmentalized shotgun assembler for the human genome
| Autor: | Clark M. Mobarry, Granger G. Sutton, Eugene W. Myers, Ian M. Dew, Arthur L. Delcher, Michael Flanigan, Aaron L. Halpern, Zhongwu Lai, Knut Reinert, Saul A. Kravitz, Daniel H. Huson, Karin A. Remington |
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| Rok vydání: | 2001 |
| Předmět: |
Statistics and Probability
Genetics Chromosomes Artificial Bacterial Shotgun sequencing Genome Human Computational Biology Genomics Shotgun Computational biology Sequence Analysis DNA Biology Biochemistry Computer Science Applications Computational Mathematics Computational Theory and Mathematics Humans Human genome Cloning Molecular Databases Nucleic Acid Molecular Biology Software |
| Zdroj: | ISMB (Supplement of Bioinformatics) |
| ISSN: | 1367-4803 |
| Popis: | Two different strategies for determining the human genome are currently being pursued: one is the “clone-by-clone” approach, employed by the publicly funded project, and the other is the “whole genome shotgun assembler” approach, favored by researchers at Celera Genomics. An interim strategy employed at Celera, called compartmentalized shotgun assembly, makes use of preliminary data produced by both approaches. In this paper we describe the design, implementation and operation of the “compartmentalized shotgun assembler”. Contact: Knut.Reinert@celera.com |
| Databáze: | OpenAIRE |
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