Results of an early intervention programme for patients with bacteraemia: analysis of prognostic factors and mortality
| Autor: | J. García-Alegría, A. Blázquez, José Luis Prada, Fernando Fernández-Sánchez, F. Rivas, A. del Arco, J. de la Torre, Julián Olalla, N. Montiel-Quezel |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Adult Male medicine.medical_specialty Pediatrics Adolescent 030106 microbiology Bacteremia lcsh:Infectious and parasitic diseases 03 medical and health sciences Young Adult 0302 clinical medicine Medical microbiology Risk Factors Early Medical Intervention Epidemiology medicine Escherichia coli Infection control Humans lcsh:RC109-216 030212 general & internal medicine Prospective Studies Young adult Mortality Prospective cohort study Escherichia coli Infections Aged Cross Infection Infection Control business.industry Middle Aged medicine.disease bacterial infections and mycoses Prognosis Hospitals Anti-Bacterial Agents Infectious Diseases Intervention programme Spain Tropical medicine Bacteraemia Female business Cohort study Research Article |
| Zdroj: | BMC Infectious Diseases BMC Infectious Diseases, Vol 17, Iss 1, Pp 1-6 (2017) |
| ISSN: | 1471-2334 |
| Popis: | Background Bacteraemia is a common cause of morbidity and mortality in patients admitted to hospital. The aim of this study is to analyse the results of a two-year programme for the early optimisation of antibiotic treatment in patients admitted to the Costa del Sol Hospital (Marbella. Spain). Methods A prospective two-year cohort study was conducted, evaluating all episodes of bacteraemia at the Costa del Sol Hospital. Epidemiological and microbiological characteristics, any modification of the initial antibiotic treatment, prognostic risk stratification, early mortality related to the episode of bacteraemia, and mortality after the seventh day, were included in the analysis. Results Seven hundred seventy-three episodes of bacteraemia were treated, 61.6% males and 38.4% females. The mean age was 65.2 years. The condition was most commonly acquired in the community (41.4%). The bacteraemia was most frequently urological in nature (30.5%), and E coli was the microorganism most frequently isolated (31.6%). In 51.1% of the episodes, a modification was made to optimise the treatment. In the first week, 8.2% died from bacteraemia, and 4.5% had died when they were located. The highest rates of death were associated with older patients, nosocomial acquisition, no source, McCabe score rapidly fatal, Charlson index ≥3, Pitt index ≥3 and treatment remained unmodified. Conclusion The existence of bacteraemia control programmes and teams composed of clinicians who are experienced in the treatment of infectious diseases, can improve the disease outcome by enabling more severe episodes of bacteraemia to be recognised and their empirical treatment optimised. |
| Databáze: | OpenAIRE |
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