Pulmonary Hypertension Secondary to COPD
| Autor: | Adil Shujaat, Abubakr A. Bajwa, James Cury |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Pulmonary and Respiratory Medicine
lcsh:RC705-779 medicine.medical_specialty COPD Elevated pulmonary artery pressure business.industry Long-term oxygen therapy Inflammation General Medicine Review Article lcsh:Diseases of the respiratory system medicine.disease Pulmonary hypertension Pathogenesis Increased risk Internal medicine medicine Cardiology Physical therapy medicine.symptom Endothelial dysfunction business |
| Zdroj: | Pulmonary Medicine, Vol 2012 (2012) Pulmonary Medicine |
| ISSN: | 2090-1844 2090-1836 |
| Popis: | The development of pulmonary hypertension in COPD adversely affects survival and exercise capacity and is associated with an increased risk of severe acute exacerbations. Unfortunately not all patients with COPD who meet criteria for long term oxygen therapy benefit from it. Even in those who benefit from long term oxygen therapy, such therapy may reverse the elevated pulmonary artery pressure but cannot normalize it. Moreover, the recent discovery of the key roles of endothelial dysfunction and inflammation in the pathogenesis of PH provides the rationale for considering specific pulmonary vasodilators that also possess antiproliferative properties and statins. |
| Databáze: | OpenAIRE |
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