Gaming for Adherence to Medication using Ehealth in Rheumatoid arthritis (GAMER) study: a randomised controlled trial

Autor: Bart P H Pouls, Charlotte L Bekker, Fatma Gundogan, Renske CF Hebing, Hein AW van Onzenoort, Liesbeth I van de Ven, Harald E Vonkeman, Rob Tieben, Johanna E Vriezekolk, Sandra van Dulmen, Bart Van den Bemt
Přispěvatelé: Rheumatology, AII - Inflammatory diseases, MUMC+: DA KFT Medische Staf (9), Clinical Pharmacy, RS: FHML non-thematic output
Rok vydání: 2022
Předmět:
Zdroj: Rheumatic & Musculoskeletal Diseases Open, 8
RMD Open, 8(2):002616. BMJ Publishing Group
Rheumatic & Musculoskeletal Diseases Open, 8, 2
Pouls, B P H, Bekker, C L, Gundogan, F, Hebing, R C F, van Onzenoort, H A W, van de Ven, L I, Vonkeman, H E, Tieben, R, Vriezekolk, J E, van Dulmen, S & van den Bemt, B 2022, ' Gaming for Adherence to Medication using Ehealth in Rheumatoid arthritis (GAMER) study : A randomised controlled trial ', RMD Open, vol. 8, no. 2, 002616 . https://doi.org/10.1136/rmdopen-2022-002616
RMD Open, 8(2). BMJ Publishing Group
ISSN: 2056-5933
DOI: 10.1136/rmdopen-2022-002616
Popis: ObjectiveTo examine the effect on adherence to disease modifying anti-rheumatic drugs (DMARDs) in participants with rheumatoid arthritis (RA) of a serious game that targeted implicit attitudes toward medication.MethodsA multicentre randomised controlled trial (RCT) was performed with adults with RA that used DMARDs and possessed a smartphone/tablet. Control and intervention groups received care as usual. The intervention group played the serious game at will during 3 months. Game play data and online questionnaires Compliance Questionnaire on Rheumatology (CQR), Beliefs about Medicine Questionnaire (BMQ), Health Assessment Questionnaire (HAQ) and Rheumatoid Arthritis Disease Activity Index (RADAI) were collected. Primary outcome was DMARD implementation adherence operationalised as the difference in proportion of non-adherent participants (ResultsOf the 110 intervention participants that started the study, 87 participants (79%) installed the game and had a median playtime of 9.7 hours at 3 months. Overall, 186 participants completed the study. Adherence in intervention group (63%) and control group (54%) did not differ significantly (p=0.13) at 3 months. Neither were there differences oberved in CQR continuous score, beliefs about medication (BMQ) or clinical outcomes (HAQ and RADAI).ConclusionA serious game aimed at reinterpreting attitudes toward medication failed to show an effect on adherence to DMARDs or clinical outcomes in patients with RA. The game was played frequently indicating that it can be an effective channel for reaching patients.Trial registration numberNL7217.
Databáze: OpenAIRE