HEPATIC OSTEODYSTROPHY IN A GOLDEN LION TAMARIN (LEONTOPITHECUS ROSALIA)
| Autor: | Sara E. Childs-Sanford, Brian G. Caserto, Noha Abou-Madi, Erica Behling-Kelly, Eunju Choi, Erin E. King, Heather Priest, Andrew D. Miller |
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| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty Leontopithecus Cirrhosis 040301 veterinary sciences Biology Hypoglycemia Chronic liver disease 0403 veterinary science 03 medical and health sciences Fatal Outcome 0302 clinical medicine biology.animal medicine Animals Lion tamarin Leontopithecus rosalia Osteomalacia General Veterinary medicine.diagnostic_test Liver Diseases Monkey Diseases Complete blood count 04 agricultural and veterinary sciences General Medicine medicine.disease biology.organism_classification Osteopenia Bone Diseases Metabolic Female 030211 gastroenterology & hepatology Animal Science and Zoology |
| Zdroj: | Journal of Zoo and Wildlife Medicine. 47:907-911 |
| ISSN: | 1937-2825 1042-7260 |
| DOI: | 10.1638/2015-0201.1 |
| Popis: | An 8-yr-old, captive, female golden lion tamarin ( Leontopithecus rosalia ) with a 6-yr history of hyperbilirubinemia was examined for inappetence and weight loss. Physical examination and blood pressure monitoring under anesthesia revealed hypothermia and hypotension, and blood work revealed hypoglycemia, markedly elevated liver enzymes, including serum alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase, and confirmed the hyperbilirubinemia. A complete blood count suggested chronic lymphoid leukemia. The animal's condition deteriorated during recovery, and the animal died despite aggressive treatment. Grossly, there was micronodular cirrhosis of the liver, severe icterus, and diffuse osteopenia of all examined bones. Microscopic examination of the liver confirmed the micronodular cirrhosis and bone lesions were compatible with diffuse osteopenia and osteomalacia. This brief communication presents a case of chronic liver disease and lesions indicative of metabolic bone disease, also known as hepatic osteodystrophy. To the authors' knowledge, this is the first documented case of hepatic osteodystrophy in the veterinary literature. |
| Databáze: | OpenAIRE |
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