Microbial Hydroxylation and Reduction of the Diterpene Psiadin
| Autor: | Farouk S. El-Feraly, Andrew T. McPhail, Abdel-Rahim S. Ibrahim, Khaled Y. Orabi, Ahmed Galal |
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| Rok vydání: | 2001 |
| Předmět: |
Models
Molecular biology Bioconversion Stereochemistry Gongronella butleri Aspergillus niger Fungi Molecular Conformation Hydroxylation biology.organism_classification General Biochemistry Genetics and Molecular Biology Kluyveromyces chemistry.chemical_compound chemistry Kluyveromyces marxianus Fermentation Cunninghamella blakesleeana Diterpenes Diterpene Spectral data Oxidation-Reduction Biotransformation Cunninghamella |
| Zdroj: | Zeitschrift für Naturforschung C. 56:216-222 |
| ISSN: | 1865-7125 0939-5075 |
| DOI: | 10.1515/znc-2001-3-408 |
| Popis: | Microbial bioconversion studies conducted on the diterpene psiadin have revealed that it was metabolized by Aspergillus niger (NRRL 2295) to give 2α-hydroxydeoxopsiadin, Cunninghamella blakesleeana (ATCC 8688a) to give 11β-hydroxypsiadin, and Cylindrocephalum aureum (ATCC 12720), Gongronella butleri (ATCC 22822), Kloeckera africana (ATCC 20111), and Kluyveromyces marxianus var. lactis (ATCC 2628) to yield 7α-hydroxypsiadin. Their structures have been established on the basis of spectral data. The structure and relative stereochemistry of 7α-hydroxypsiadin was confirmed by single-crystal X-ray analysis. |
| Databáze: | OpenAIRE |
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