Determinants of right ventricular outflow tract conduit longevity: a multinational analysis

Autor: Kimberlee Gauvreau, Jaap Ottenkamp, Marieke B.A. Niemantsverdriet, Mark G. Hazenkamp, Kathy J. Jenkins, Pedro J. del Nido
Přispěvatelé: Amsterdam Cardiovascular Sciences, Paediatric Cardiology
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Adult
Heart Defects
Congenital
Heart Septal Defects
Ventricular
Male
medicine.medical_specialty
Adolescent
Heart Ventricles
Transposition of Great Vessels
Persistent truncus arteriosus
Ventricular Outflow Obstruction
Risk Factors
medicine.artery
Internal medicine
medicine
Ventricular outflow tract
Humans
Transplantation
Homologous
Radiology
Nuclear Medicine and imaging
cardiovascular diseases
Child
health care economics and organizations
Tetralogy of Fallot
Retrospective Studies
Bioprosthesis
business.industry
Infant
Newborn
Infant
General Medicine
medicine.disease
Cardiac surgery
Surgery
Transplantation
Pulmonary Valve Stenosis
Treatment Outcome
surgical procedures
operative
Great arteries
Pulmonary Atresia
Child
Preschool
Pediatrics
Perinatology and Child Health
Pulmonary artery
Cardiology
cardiovascular system
Female
Cardiology and Cardiovascular Medicine
Pulmonary atresia
business
Zdroj: Congenital heart disease, 3(3), 176-184. Wiley-Blackwell
ISSN: 1747-079X
Popis: Objective. The need for conduit replacement in the growing child remains a major problem after right ventricular outflow tract reconstruction. We compared two diverse surgical centers with considerable practice variation in Europe and the United States to identify modifiable risk factors that can increase conduit longevity. Design. Retrospective analysis of 194 patients (56 Europe, 138 United States) who underwent primary right ventricular to pulmonary artery conduit placement between January 1987 and March 2003. Patients. Diagnoses included tetralogy of Fallot with pulmonary atresia, truncus arteriosus, transposition of the great arteries with ventricular septal defect and pulmonary stenosis, and double-outlet right ventricle. Results. Median age was 7.3 months (range 2 days–29.9 years). Types of conduits included aortic homografts (n = 111), pulmonary homografts (n = 48), Contegra conduits (Medtronic, Inc, Minneapolis, MN) (n = 23), and synthetic conduits (n = 12). Freedom from conduit failure at 5 years was 50% (58% Europe, 48% United States, P = NS). On multivariate analysis, smaller conduit diameter (hazard ratio [HR] 1.15, P
Databáze: OpenAIRE
Externí odkaz: