CONTROL BY OVARIAN HORMONES OF THE INFLAMMATORY RESPONSE IN THE SHEEP UTERUS

Autor: E C Leffel, T H Brinsfield, H W Hawk
Rok vydání: 1963
Předmět:
Zdroj: Reproduction. 6:79-86
ISSN: 1741-7899
1470-1626
DOI: 10.1530/jrf.0.0060079
Popis: Oestrous, luteal-phase and ovariectomized ewes were inoculated in the uterine lumen with Escherichia coli and killed 2, 4, 8 or 16 hr later. Intense leucocytic responses and closely associated bactericidal activity occurred within 4 hr in ovariectomized ewes, within 8 hr in oestrous ewes and within 16 hr in luteal-phase ewes. Intense leucocytic emigration was inhibited for 2 to 3 hr in oestrous ewes and considerably longer in luteal-phase ewes. No evidence was found that hormones inhibited the passage of extravasated leucocytes through endometrial stroma. The incubation of E. coli in excised uteri failed to indicate that non-cellular bactericidal factors were normally present in uterine lumens of ovariectomized ewes.
Databáze: OpenAIRE