Multiple sexual partners and mother-to-child transmission of HIV-1
| Autor: | Abel Dushimimana, Alfred J. Saah, Jean-Baptiste Kurawige, Paula Nawrocki, Phocas Habimana, Ann Chao, Felicite Musanganire, Marc Bulterys |
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| Rok vydání: | 1993 |
| Předmět: |
Sexual partner
medicine.medical_specialty Unprotected Sexual Intercourse Immunology Population CD4-CD8 Ratio HIV Infections Acquired immunodeficiency syndrome (AIDS) Pregnancy Risk Factors medicine Immunology and Allergy Humans Sex organ Risk factor Pregnancy Complications Infectious education Gynecology education.field_of_study business.industry Obstetrics Infant Newborn Infant Odds ratio medicine.disease Infectious Diseases Sexual Partners HIV-1 Female business |
| Zdroj: | AIDS (London, England). 7(12) |
| ISSN: | 0269-9370 |
| Popis: | This study sought to investigate risk factors for mother-to-child transmission of HIV-1 particularly sexual behavior before and during pregnancy. This study is part of a prospective cohort studying Butare Rwanda of 318 HIV-1-seropositive and 309 HIV-1-seronegative women enrolled during pregnancy and followed for a mean duration of 21 months (range 8-34 months). Clinical follow-up of the mother-infant pairs was performed at 6-week intervals during the first year of life and at 4-months intervals thereafter. Detailed sexual history interviews were conducted during pregnancy and at the first postnatal visit. Of 184 singleton infants born to HIV-1 infected mothers who survived the neonatal period. 32 (17%) children were classified as HIV-1-infected and 22 (12%) died with indeterminate HIV-1 infection status. The vertical transmission rate was estimated to be between 20 and 29%. Unprotected sexual intercourse with increased number of partners during the past 5 years was strongly associated with mother-to-child transmission to (p |
| Databáze: | OpenAIRE |
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