Chest radiograph features of multisystem inflammatory syndrome in children (MIS-C) compared to pediatric COVID-19

Autor: Edward J Richer, Jay Shah, Sarah S Milla, Adina Alazraki, Erica L. Riedesel, Leann E Linam, Christina A. Rostad, Bradley S. Rostad, Preeti Jaggi
Rok vydání: 2021
Předmět:
Male
medicine.medical_specialty
Adolescent
Radiography
030218 nuclear medicine & medical imaging
Diagnosis
Differential
03 medical and health sciences
0302 clinical medicine
Abdomen
Multisystem inflammatory syndrome in children
Ultrasound
Medical imaging
Humans
Medicine
Radiology
Nuclear Medicine and imaging
Pediatrics
Perinatology
and Child Health
Child
Children
Computed tomography
Lung
Retrospective Studies
Neuroradiology
Coronavirus disease 2019
medicine.diagnostic_test
SARS-CoV-2
business.industry
COVID-19
Infant
Retrospective cohort study
respiratory system
Systemic Inflammatory Response Syndrome
respiratory tract diseases
medicine.anatomical_structure
Radiology Nuclear Medicine and imaging
Child
Preschool
Pediatrics
Perinatology and Child Health
Chest
Original Article
Female
Radiography
Thoracic
Radiology
Differential diagnosis
business
Chest radiograph
030217 neurology & neurosurgery
Zdroj: Pediatric Radiology
ISSN: 1432-1998
0301-0449
DOI: 10.1007/s00247-020-04921-9
Popis: Background Although the radiographic features of coronavirus disease 2019 (COVID-19) in children have been described, the distinguishing features of multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 are not well characterized. Objective We compared the chest radiographic findings of MIS-C with those of COVID-19 and described other distinguishing imaging features of MIS-C. Materials and methods We performed a retrospective case series review of children ages 0 to 18 years who were hospitalized at Children’s Healthcare of Atlanta from March to May 2020 and who either met the Centers for Disease Control and Prevention (CDC) case definition for MIS-C (n=11) or who had symptomatic, laboratory-confirmed COVID-19 (n=16). Two radiologists reviewed the most severe chest radiographs for each patient. The type and distribution of pulmonary opacities and presence or absence of pleural effusions were recorded. The chest radiographs were categorized based on potential COVID-19 imaging findings as typical, indeterminate, atypical or negative. An imaging severity score was also assigned using a simplified version of the Radiographic Assessment of Lung Edema Score. Findings were statistically compared between patients with MIS-C and those with COVID-19. Additional imaging findings of MIS-C were also described. Results Radiographic features of MIS-C included pleural effusions (82% [9/11]), pulmonary consolidations (73% [8/11]) and ground glass opacities (91% [10/11]). All of the lung opacities (100% [10/10]) were bilateral, and the majority of the pleural effusions (67% [6/9]) were bilateral. Compared to children with COVID-19, children with MIS-C were significantly more likely to develop pleural effusions on chest radiograph (82% [9/11] vs. 0% [0/0], P-value
Databáze: OpenAIRE
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