Clinical features and disease severity in an Iranian population of inpatients with COVID-19
| Autor: | Sahar Ravanshad, Fariba Rezaeetalab, Ahmadreza Zarifian, Sepide Hejazi, Shohre Khatami, Reza Basiri, Mina AkbariRad, Mahnaz Mozdourian, Neda Saeedian, Shima Nabavi, Zahra Javidarabshahi, Maryam Emadzadeh, Abolghasem Allahyari, Farnoosh Ebrahimzadeh, Mohammad Ramezani, Maryam Miri, Mohsen Seddigh-Shamsi |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty ARDS Nausea Science Diseases Comorbidity macromolecular substances 030204 cardiovascular system & hematology Iran Severity of Illness Index Article law.invention Sepsis 03 medical and health sciences 0302 clinical medicine Medical research law Internal medicine Severity of illness Coagulopathy Medicine Humans 030212 general & internal medicine Signs and symptoms Aged Inpatients Multidisciplinary business.industry Age Factors COVID-19 Middle Aged medicine.disease Intensive care unit C-Reactive Protein Cross-Sectional Studies Risk factors Vomiting Female medicine.symptom business Tomography X-Ray Computed Biomarkers |
| Zdroj: | Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021) Scientific Reports |
| ISSN: | 2045-2322 |
| Popis: | Coronavirus disease 2019 (COVID-19) can present with a variety of symptoms. Severity of the disease may be associated with several factors. Here, we review clinical features of COVID-19 inpatients with different severities. This cross-sectional study was performed in Imam Reza hospital, Mashhad, Iran, during February–April 2020. COVID-19 patients with typical computed tomography (CT) patterns and/or positive reverse-transcriptase polymerase chain reaction (RT-PCR) were included. The patients were classified into three groups of moderate, severe, and critical based on disease severity. Demographic, clinical, laboratory, and radiologic findings were collected and compared. P 2 saturation, extent of CT involvement, serum C-reactive protein (CRP), pH, pO2, and aspartate transaminase (P 2 saturation, nausea/vomiting, and extent of lung CT involvement were independent predictors of severe/critical COVID-19 (OR 0.342, 45.93, and 25.48, respectively; P 2 saturation, nausea/vomiting, and extent of lung CT involvement as independent predictors of severe COVID-19 conditions. Serum CRP levels and pO2 were also considerably higher patients with higher severity and can be used along with other factors to predict severe disease in COVID-19 patients. |
| Databáze: | OpenAIRE |
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