Production of Virus by Embryonic Cultures co-cultivated with Breast Tumour Cells or infected with Milk from Breast Cancer Patients
| Autor: | E. Harel, Z. Gilead, S. Karby, J. Keydar |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Adult
Pleural effusion DNA polymerase viruses Breast Neoplasms Adenocarcinoma Tritium General Biochemistry Genetics and Molecular Biology Virus Cell Line Breast cancer Pregnancy Centrifugation Density Gradient medicine Humans RNA Viruses Breast Uridine Aged Milk Human biology Nucleic Acid Hybridization RNA Cancer RNA-Directed DNA Polymerase General Medicine Middle Aged Embryo Mammalian medicine.disease Embryonic stem cell Molecular biology Oncornavirus biology.protein RNA Viral Female Oncogenic Viruses |
| Zdroj: | Nature New Biology. 241:49-52 |
| ISSN: | 2058-1092 0090-0028 |
| DOI: | 10.1038/newbio241049a0 |
| Popis: | VIRIONS morphologically similar to mouse mammary tumour virus (MMTV) have been found by electron microscopy of human milk samples1–4, and in thin sections of breast tumour tissue, and of pleural effusion cells from breast cancer patients5. Viruses isolated from human milk have similarities to those of the oncornavirus group a, a buoyant density in a sucrose: gradient (1.16–1.19 g ml.−)1; b, the presence of the RNA-dependent DNA polymerase or “reverse transcriptase”6–9; c, the existence of 60S-70S RNA template in the virions10,11. |
| Databáze: | OpenAIRE |
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