Dengue fever complicated with Guillain-Barré syndrome: a case report and review of the literature
| Autor: | John Shelton, Mahendra Ekanayake, Chamara Dalugama, Indika Gawarammana |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
Weakness Pediatrics medicine.medical_specialty Fever lcsh:Medicine Case Report Respiratory failure Dengue virus Guillain-Barre Syndrome medicine.disease_cause Dengue fever Malaise Dengue 03 medical and health sciences 0302 clinical medicine medicine Humans Guillan-Barré syndrome 030212 general & internal medicine Sri Lanka Leukopenia biology Guillain-Barre syndrome business.industry lcsh:R Immunoglobulins Intravenous General Medicine Middle Aged medicine.disease Arthralgia Treatment Outcome Immunoglobulin M biology.protein medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Medical Case Reports, Vol 12, Iss 1, Pp 1-4 (2018) Journal of Medical Case Reports |
| ISSN: | 1752-1947 |
| DOI: | 10.1186/s13256-018-1626-y |
| Popis: | Background Dengue is an arboviral infection classically presenting with fever, arthralgia, headache, and rashes. It is hyperendemic in Sri Lanka and has a major impact on health. Neurological complications of dengue fever are rare but have been reported in the literature. Case presentation A 60-year-old Sri Lankan man presented with a history of fever, arthralgia, and generalized malaise of 2 days duration. A diagnosis of dengue was confirmed with leukopenia, thrombocytopenia, and positive NS1 antigen done on day 2 without evidence of hemoconcentration. On admission, our patient had weakness of the bilateral lower limbs, which progressed in an ascending pattern involving both upper limbs and neck muscles, requiring assisted ventilation. Electromyography confirmed a demyelinating polyneuropathy and cerebrospinal fluid showed albumincytological dissociation. He was treated with intravenous immunoglobulins and made an uneventful recovery. Subsequently, his immunoglobulin M test result for dengue virus was positive. Conclusions Guillain-Barré syndrome is a rare but possible neurological sequel following dengue fever. In regions where dengue is hyperendemic, screening for dengue illness may be important in patients presenting with acute flaccid paralysis. |
| Databáze: | OpenAIRE |
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