Meta-analysis of the outcomes of intramedullary nailing and plate fixation of humeral shaft fractures

Autor: Qing-gang Zhang, Guoxin Nan, Hong-wei Chen, Le-shun Zhou, Jian-wen Gu, Shan Ou, Guo-dong Liu, Jun Fei
Rok vydání: 2013
Předmět:
Zdroj: International Journal of Surgery. 11(9):864-868
ISSN: 1743-9191
DOI: 10.1016/j.ijsu.2013.08.002
Popis: ObjectiveThe purpose of this study is to compare the outcomes of intramedullary nailing and plate fixation in the treatment of humeral shaft fractures using meta-analysis.MethodsPubMed, MEDLINE, EMBASE, the Cochrane Controlled Clinical Trials Register (CCTR) databases were searched for studies that investigated the efficacy of intramedullary nailing and plate fixation in the management of humeral shaft fractures. Delayed healing rate, nonunion, postoperative infection and radial nerve paralysis were key outcomes of interest. Data were searched within the time period of July 1990 through September 2012. The statistical software RevMan 5.0 was used to analyze the statistical significance of the results.ResultsTotal 459 cases of patients in 10 literature, including 231 cases of plate group and 228 cases of the intramedullary nailing groups were collected. The results of meta-analysis showed that delayed healing rate of humeral shaft fractures was lower in plate fixation compared with intramedullary nailing (RR = 2.64, 95% CI (1.08, 6.49), P 0.05).ConclusionsIn general, the effect size of intramedullary nailing may be comparable to that of plate fixation in the terms of nonunion, postoperative infections, radial nerve paralysis. The only slightly difference was identified in the event of delayed healing rate.
Databáze: OpenAIRE