Clinical application of exhaled nitric oxide measurement in pediatric lung diseases
Autor: | Francesca Santamaria, Margherita Varini, Francesco Sperlì, Carlotta Povesi Dascola, Marco Maglione, Carlo Caffarelli, Angelo Manna, Silvia Montella |
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Přispěvatelé: | Manna, Angelo, Caffarelli, Carlo, Varini, Margherita, Dascola, Carlotta Povesi, Montella, Silvia, Maglione, Marco, Sperlì, Francesco, Santamaria, Francesca |
Jazyk: | angličtina |
Předmět: |
Lung Diseases
medicine.medical_specialty Prognosi Predictive Value of Test Review Nitric Oxide Lung Disease Sensitivity and Specificity Severity of Illness Index Exhaled nitric oxide Bronchiectasi Community-acquired pneumonia Predictive Value of Tests Forced Expiratory Volume Airway disease medicine Humans Bronchioliti Child Intensive care medicine Airway diseases Children Asthma Lung Bronchiectasis business.industry lcsh:RJ1-570 lcsh:Pediatrics Biomarker respiratory system Prognosis medicine.disease Community acquired pneumonia respiratory tract diseases Pneumonia medicine.anatomical_structure Bronchiolitis Pediatrics Perinatology and Child Health Airway business Biomarkers Diffuse lung disease Human |
Zdroj: | Italian Journal of Pediatrics Italian Journal of Pediatrics, Vol 38, Iss 1, p 74 (2012) |
ISSN: | 1824-7288 |
DOI: | 10.1186/1824-7288-38-74 |
Popis: | Summary Fractional exhaled nitric oxide (FeNO) is a non invasive method for assessing the inflammatory status of children with airway disease. Different ways to measure FeNO levels are currently available. The possibility of measuring FeNO levels in an office setting even in young children, and the commercial availability of portable devices, support the routine use of FeNO determination in the daily pediatric practice. Although many confounding factors may affect its measurement, FeNO is now widely used in the management of children with asthma, and seems to provide significantly higher diagnostic accuracy than lung function or bronchial challenge tests. The role of FeNO in airway infection (e.g. viral bronchiolitis and common acquired pneumonia), in bronchiectasis, or in cases with diffuse lung disease is less clear. This review focuses on the most recent advances and the current clinical applications of FeNO measurement in pediatric lung disease. |
Databáze: | OpenAIRE |
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