Chronic Vasculitis and Polyneuropathy due to Infection with Bartonella henselae
| Autor: | D. Heuss, T. Harrer, P. Frangou, B. Stockmeyer, T. Moriabadi, Christoph Schoerner |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Vasculitis Microbiology (medical) Pathology medicine.medical_specialty Hyperkeratosis Polyneuropathies Recurrence Biopsy medicine Humans Foot Ulcer Bartonella henselae medicine.diagnostic_test biology business.industry Cat-scratch disease General Medicine Angiomatosis medicine.disease biology.organism_classification Bacillary angiomatosis Infectious Diseases Chronic Disease Angiomatosis Bacillary business Polyneuropathy |
| Zdroj: | Infection. 35:107-109 |
| ISSN: | 1439-0973 0300-8126 |
| DOI: | 10.1007/s15010-007-6021-3 |
| Popis: | Bartonella henselae, the causative agent of cat scratch disease and bacillary angiomatosis, is associated with an expanding spectrum of diseases. Here, we report on a 40-year-old patient suffering from chronic recurrent painful ulcers of the toes, distal axonal sensomotor polyneuropathy and Raynaud's phenomenon. Biopsy of the sural nerve demonstrated an axonal neuropathy with a neurogenic muscular atrophy. Treatment with high dose corticosteroids had no beneficial effect. A biopsy taken from a recurring ulcer 7 years after the beginning of the disease revealed superficial ulcerated hyperkeratosis with subepithelial proliferation of small vessels compatible with a diagnosis of verruca peruana, however, without detection of microorganism. Serologic analysis revealed an elevated IFT titer of 1:1,024 against B. henselae. Treatment with erythromycin induced healing of the ulcer, remission of the vasculitis and the polyneuropathy, and a decline of the IFT titer. This case illustrates that B. henselae infection should be considered in patients with vasculitis and polyneuropathic syndromes. |
| Databáze: | OpenAIRE |
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