Predictors of smoking lapse in a human laboratory paradigm

Autor: Lara A. Ray, Daniel J. O. Roche, Iris Y. Guzman, Spencer Bujarski, Nathasha R. Moallem, Jenessa R. Shapiro
Rok vydání: 2014
Předmět:
Male
Future studies
Craving
Severity of Illness Index
Medical and Health Sciences
Smoking behavior
Substance Misuse
Primary outcome
Recurrence
Risk Factors
epidemiology [Smoking]
psychology [Substance Withdrawal Syndrome]
Psychology
Smoking lapse
Nicotine dependence
media_common
Ad libitum smoking
Psychiatry
Abstinence
Smoking
Tobacco Use Disorder
Middle Aged
Substance Withdrawal Syndrome
Reinforcement
Withdrawal
Respiratory
Female
medicine.symptom
Reinforcement
Psychology

Adult
medicine.medical_specialty
media_common.quotation_subject
Human laboratory model
rehabilitation
Young Adult
Clinical Research
Tobacco
Behavioral and Social Science
medicine
Humans
psychology [Smoking Cessation]
Pharmacology
Tobacco Smoke and Health
Prevention
Psychology and Cognitive Sciences
medicine.disease
Brain Disorders
Clinical trial
Affect
Mood
Good Health and Well Being
Smoking Cessation
Drug Abuse (NIDA only)
psychology [Tobacco Use Disorder]
Zdroj: Psychopharmacology, vol 231, iss 14
Roche, DJO; Bujarski, S; Moallem, NR; Guzman, I; Shapiro, JR; & Ray, LA. (2014). Predictors of smoking lapse in a human laboratory paradigm. Psychopharmacology, 231(14), 2889-2897. doi: 10.1007/s00213-014-3465-x. UCLA: Retrieved from: http://www.escholarship.org/uc/item/2964n4c5
Roche, DJO; Bujarski, S; Moallem, NR; Guzman, I; Shapiro, JR; & Ray, LA. (2014). Predictors of smoking lapse in a human laboratory paradigm. Psychopharmacology, 1-9. doi: 10.1007/s00213-014-3465-x. UCLA: Retrieved from: http://www.escholarship.org/uc/item/78j7p18h
DOI: 10.1007/s00213-014-3465-x.
Popis: Rationale: During a smoking quit attempt, a single smoking lapse is highly predictive of future relapse. While several risk factors for a smoking lapse have been identified during clinical trials, a laboratory model of lapse was until recently unavailable and, therefore, it is unclear whether these characteristics also convey risk for lapse in a laboratory environment. Objectives: The primary study goal was to examine whether real-world risk factors of lapse are also predictive of smoking behavior in a laboratory model of smoking lapse. Methods: After overnight abstinence, 77 smokers completed the McKee smoking lapse task, in which they were presented with the choice of smoking or delaying in exchange for monetary reinforcement. Primary outcome measures were the latency to initiate smoking behavior and the number of cigarettes smoked during the lapse. Several baseline measures of smoking behavior, mood, and individual traits were examined as predictive factors. Results: Craving to relieve the discomfort of withdrawal, withdrawal severity, and tension level were negatively predictive of latency to smoke. In contrast, average number of cigarettes smoked per day, withdrawal severity, level of nicotine dependence, craving for the positive effects of smoking, and craving to relieve the discomfort of withdrawal were positively predictive of number of cigarettes smoked. Conclusions: The results suggest that real-world risk factors for smoking lapse are also predictive of smoking behavior in a laboratory model of lapse. Future studies using the McKee lapse task should account for between subject differences in the unique factors that independently predict each outcome measure. © 2014 Springer-Verlag Berlin Heidelberg.
Databáze: OpenAIRE