Chemical Composition and Topology of Poly(lactide-co-glycolide) Revealed by Pushing MALDI-TOF MS to Its Limit
Autor: | Saskia Huijser, Robbert Duchateau, Juan Huang, Bbp Bastiaan Staal, CE Cor Koning |
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Přispěvatelé: | Chemical Engineering and Chemistry |
Rok vydání: | 2006 |
Předmět: |
chemistry.chemical_classification
Magnetic Resonance Spectroscopy Lactide Polymers Analytical chemistry General Medicine General Chemistry Polymer Topology Mass spectrometry Ring-opening polymerization Catalysis Matrix-assisted laser desorption/ionization chemistry.chemical_compound Polylactic Acid-Polyglycolic Acid Copolymer chemistry Polymerization Tin Spectrometry Mass Matrix-Assisted Laser Desorption-Ionization Copolymer Lactic Acid Polyglycolic Acid Topology (chemistry) |
Zdroj: | Angewandte Chemie-International Edition, 45(25), 4104-4108. Wiley |
ISSN: | 1521-3773 1433-7851 0570-0833 |
DOI: | 10.1002/anie.200600594 |
Popis: | Software developed in house in combination with a recently developed method of MALDI-TOF MS enable not only the elucidation of individual chain structures of poly(lactide-co-glycolide), a polymer used extensively in the medical sector, but a full characterization of this copolymer including even its chemical composition and topology (random, gradient, block (see figure), or alternating). |
Databáze: | OpenAIRE |
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