Using the DOSE index to predict changes in health status of patients with COPD: a prospective cohort study
Autor: | Saskia van den Haak-Rongen, Lisette van den Bemt, Myrte Rolink, Wouter D. van Dijk, Willem Pieters, Tjard Schermer |
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Rok vydání: | 2013 |
Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Index (economics) Health Status Pulmonary disease Primary care Severity of Illness Index Pulmonary Disease Chronic Obstructive Risk Factors Forced Expiratory Volume Internal medicine medicine Humans In patient Prospective Studies Prospective cohort study Aged COPD Primary Health Care business.industry Smoking Public Health Environmental and Occupational Health Effective primary care and public health [NCEBP 7] Middle Aged medicine.disease Effective primary care and public health Poverty-related infectious diseases [NCEBP 7] Dyspnea Treatment Outcome Editorial Physical therapy Population study Smoking status business |
Zdroj: | Primary Care Respiratory Journal, 22, 169-174 Primary Care Respiratory Journal, 22, 2, pp. 169-174 Primary Care Respiratory Journal: Journal of the General Practice Airways Group |
ISSN: | 1475-1534 1471-4418 |
DOI: | 10.4104/pcrj.2013.00033 |
Popis: | Item does not contain fulltext BACKGROUND: The severity of chronic obstructive pulmonary disease (COPD) should not be based on the level of airflow limitation alone. A multicomponent index such as the DOSE index (dyspnoea score (D), level of airflow obstruction (O), current smoking status (S), and exacerbations (E)) has the potential to predict important future outcomes in patients with COPD more effectively than the forced expiratory volume in one second. Health status deterioration should be prevented in COPD patients. AIMS: To investigate whether the DOSE index can predict which patients are at risk of a clinically relevant change in health status. METHODS: A prospective cohort study was performed using data from primary and secondary care. The DOSE score was determined at baseline and the 2-year change in the Clinical COPD Questionnaire (CCQ) score was calculated. Linear regression analysis was performed for the effect of a high DOSE score (>/=4) on the change in CCQ score. RESULTS: The study population consisted of 209 patients (112 patients from primary care). Overall, a high DOSE score was a significant predictor of a change in CCQ score after 2 years (0.41, 95% CI 0.13 to 0.70), particularly in primary care patients. CONCLUSIONS: A DOSE score of >/=4 has the ability to identify COPD patients with a greater risk of future worsening in health status. 6 p. |
Databáze: | OpenAIRE |
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