Effect of synthetic colloidal nanoparticles in acrylic resin of dental use

Autor: RA Fernandes, Douglas Roberto Monteiro, Emerson R. Camargo, Renata L. Sala, Tatielih Pardim Oliveira Xavier, Francisco Nunes de Souza Neto, Alberto Carlos Botazzo Delbem, Caio M. Paranhos, Sandra Andrea Cruz, Debora Barros Barbosa
Přispěvatelé: Universidade Federal de São Carlos (UFSCar), Universidade Estadual Paulista (Unesp), Federal Institute of Education Science and Technology of Goias – Campus Uruaçu (IFG), University of Western São Paulo (UNOESTE)
Rok vydání: 2019
Předmět:
Zdroj: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
ISSN: 0014-3057
Popis: Made available in DSpace on 2019-10-06T16:03:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-03-01 Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Acrylic resin employed in dental materials can act as substrate for microorganisms’ adhesion and biofilm formation. To overcome this, silver nanoparticles (AgNPs) were combined with poly(methyl methacrylate) (PMMA) to reduce denture stomatitis caused by Candida glabrata. Although AgNPs antimicrobial activity is already known, the physicochemical properties of its nanocomposites, which dictate the performance of these commercial targets remain little explored. We evaluated the effect of different amount of AgNPs in PMMA obtained by the thermal polymerization. Among the mechanical tests employed, PMMA flexural strength decreased with higher AgNPs concentration. The microbiological adhesion test against Candida glabrata revealed the nanocomposite with 0.05% of AgNPs has greater capacity to inhibit the biofilm formed on its surface. Although we observed distinct thermo-mechanical behavior in the presence of AgNPs, antimicrobial property was not linearly dependent of nanoparticles concentration and was influenced by nanoparticles dispersion and distribution in the polymer matrix. Federal University of São Carlos (UFSCar) Department of Chemistry Interdisciplinary Laboratory of Electrochemistry and Ceramics (LIEC), Rod. Washington Luis, Km 235 State University of São Paulo (UNESP) Araçatuba Dental School Department of Pediatric Dentistry and Public Health, Rua José Bonifácio 1193 Federal Institute of Education Science and Technology of Goias – Campus Uruaçu (IFG), Rua Formosa, Qd 28 e 29, Loteamento Santana Graduate Program in Dentistry (GPD) – Master's Degree University of Western São Paulo (UNOESTE), Rua José Bongiovani 700 State University of São Paulo (UNESP) Araçatuba Dental School Department of Pediatric Dentistry and Public Health, Rua José Bonifácio 1193 FAPESP: 2012/07067-0 FAPESP: 2012/17880-0 FAPESP: 2015/13958-3
Databáze: OpenAIRE