Outcome of Surgical Correction of Congenital Supravalvular Aortic Stenosis With Two- and Three-Sinus Reconstruction Techniques
| Autor: | Felix Berger, Vladimir Alexi-Meskishvili, Roland Hetzer, Peter Kramer, Joachim Photiadis, Daniel Absi |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Adolescent Peak pressure Hemodynamics Young Adult medicine Humans Child Sinus (anatomy) Retrospective Studies business.industry Infant Middle Aged Surgical correction medicine.disease Surgery Aortic Stenosis Supravalvular Survival Rate Stenosis Treatment Outcome medicine.anatomical_structure Child Preschool Concomitant Female Congenital supravalvular aortic stenosis Cardiology and Cardiovascular Medicine business Vascular Surgical Procedures Supravalvular aortic stenosis |
| Zdroj: | The Annals of Thoracic Surgery. 97:634-640 |
| ISSN: | 0003-4975 |
| DOI: | 10.1016/j.athoracsur.2013.09.083 |
| Popis: | Background Several surgical techniques for the treatment of congenital supravalvular aortic stenosis have been developed, yet there is no consensus about the optimal approach. We reviewed our institutional experience with 2- and 3-sinus reconstruction techniques. Methods Thirty-eight patients operated on for supravalvular aortic stenosis between 1987 and 2012 in our institution were analyzed retrospectively. Eight patients (21%) were infants and in 5 (13.2%) diffuse stenosis was present. Mean peak pressure gradient was 86.1 ± 28.7 mm Hg preoperatively. Surgical procedures included single-patch enlargement (McGoon, n = 3), inverted bifurcated-patch aortoplasty (Doty, n = 22), 3-sinus patch augmentation (Brom, n = 8), and autologous slide aortoplasty (n = 5). Major concomitant procedures were performed in 10 patients (26.3%). Results Early mortality was 2.6%. Follow-up continued for a median of 7.5 years (range 3 weeks to 22 years). Overall survival estimates were 94% and 90% and overall freedom from reoperation was 83% at 5 and 20 years, respectively. No differences were found between surgical techniques in respect to survival, clinical course, hemodynamic outcome, or freedom from reoperation rates. A significantly worse outcome in regard to survival and reoperation rates was observed in infants. Conclusions Our study demonstrates equally good results for the repair of supravalvular aortic stenosis with both 2- and 3-sinus reconstruction. No evidence of a superior outcome for 3-sinus reconstruction techniques was found. Operation in infancy is an important factor associated with unfavorable outcome. |
| Databáze: | OpenAIRE |
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