Determination of perfluoroalkyl substances (PFASs) in fats and oils by QuEChERS/micro-HPLC-MS/MS
| Autor: | Magdalena Surma, Mariusz K. Piskula, Katarzyna Sznajder-Katarzyńska, Wiesław Wiczkowski |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0303 health sciences
Fluorocarbons Sorbent Chromatography 030309 nutrition & dietetics Extraction (chemistry) Relative standard deviation Solid Phase Extraction 04 agricultural and veterinary sciences Polish population Quechers 040401 food science 03 medical and health sciences chemistry.chemical_compound 0404 agricultural biotechnology chemistry Liquid chromatography–mass spectrometry Tandem Mass Spectrometry Perfluorooctanoic acid Humans Micro hplc Oils Chromatography High Pressure Liquid Food Science |
| Zdroj: | Food research international (Ottawa, Ont.). 137 |
| ISSN: | 1873-7145 |
| Popis: | Per- and polyfluoroalkyl substances (PFASs) are man-made chemicals that have been identified as global pollutants. Their widespread occurrence, including in food, is a potential concern for consumers. This work focuses on the application of a simple and reliable analytical method for the simultaneous determination of ten perfluoroalkyl acids in highly complex fatty matrices (fats and oils). The perfluoroalkyl substances were extracted by the QuEChERS method, based on the dispersive-Solid Phase Extraction using styrene–divinylbenzene bulk sorbent, and quantitatively analysed by micro-high performance liquid chromatography tandem mass spectrometry. Recoveries ranged from 72 to 104% with an acceptable relative standard deviation below 10%. Limits of quantification were within the range 0.002–0.075 ng/g depending on the perfluoroalkyl compound. The most predominant compound in fat and oil food samples was perfluorooctanoic acid (PFOA) with a detection frequency of 100%, and the highest levels were found for perfluorobutanoic acid (PFBA). The estimated exposure to PFOA, which was 46% and 19% of the existing TWI for the EU and Polish population, respectively, is relatively high and indicates a potential risk to human health. |
| Databáze: | OpenAIRE |
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