Age-Related Differences of Blood Pressure Profile in Essential Hypertension
| Autor: | Fabio Chirilto, Anna Hölzl, Francesco Bazzanini, Pietro Biondi, G. F. Musacci, Carlo Longhini, Daniela Scorzoni, Maria Cristiana Brunazzi |
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| Rok vydání: | 1997 |
| Předmět: |
Adult
Aging medicine.medical_specialty Evening Physiology Hemodynamics Blood Pressure Essential hypertension Risk Factors Physiology (medical) Internal medicine Age related medicine Humans cardiovascular diseases Circadian rhythm Aged Morning Aged 80 and over Chronobiology Fourier Analysis business.industry Models Cardiovascular Middle Aged medicine.disease Circadian Rhythm Blood pressure Endocrinology Cardiovascular Diseases Hypertension business circulatory and respiratory physiology |
| Zdroj: | Chronobiology International. 14:397-407 |
| ISSN: | 1525-6073 0742-0528 |
| DOI: | 10.3109/07420529709001460 |
| Popis: | The purpose was to assess age-related circadian changes of blood pressure profile (BPP) employing a truncated Fourier series with four harmonics (tFs) in patients with essential hypertension. The study was performed on 32 patients with essential hypertension divided in two groups: (A) 15 patients younger than 55 years and (B) 17 patients older than 60 years. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were monitored every 20 minutes for 24 h with a noninvasive portable device (SpaceLabs 90202). To evaluate the existence of SBP and DBP circadian rhythms a one-sample runs-test was performed and the mesor, amplitude, and acrophase from the overall curve of each patient were obtained by tFs. In both groups, SBP and DBP profiles showed a first peak in the late morning and a second peak in the early evening around the same hours. The two peaks in the SBP profile were higher and the two peaks in the DBP profile were lower in older patients than in younger ones (p.01, p.05, p.3, p.05). The truncated Fourier series with four harmonics evidences different age-related BP profiles characterized by two peaks with higher SBP and lower DBP in elderly patients. These changes of BPP are in accordance with the reported higher risk of cardiovascular events observed around the same hours. |
| Databáze: | OpenAIRE |
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