Waldenström’s Macroglobulinemia Associated With AA Amyloidosis

Autor: Donald A. Kristt, Ariel Schwartz, J. Gardyn, Rivka Gal, Amos Cohen, U. Lewinski
Rok vydání: 2001
Předmět:
Zdroj: International Journal of Hematology. 74:76-78
ISSN: 1865-3774
0925-5710
Popis: It is widely accepted that amyloidosis in Waldenström's macroglobulinemia (WM) is exclusively due to amyloid light-chain deposition. However, only a small number of previous reports have actually characterized the type of amyloid in WM. We now report the third patient with WM and amyloid A protein (AA) amyloidosis. This patient developed malabsorption, nephrotic syndrome, and orthostatic hypotension. AA was immunohistochemically demonstrated in the rectal biopsy. In conjunction with previous examples of AA amyloidosis, the present report raises the possibility that AA amyloidosis may also occur in WM patients.
Databáze: OpenAIRE