Striatal Nondopaminergic Neurons: Possible Involvement in Feeding and Drinking Behavior
| Autor: | M.C. Scally, Loy D. Lytle, Douglas J. Pettibone, Ismael Ulus, Nathan Kaufman, Edwin Meyer |
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| Rok vydání: | 1978 |
| Předmět: |
Male
Kainic acid Pyrrolidines Dopamine Posture Drinking Behavior Biology Choline O-Acetyltransferase chemistry.chemical_compound medicine Animals Kainic Acid Multidisciplinary Behavior Animal Dose-Response Relationship Drug Glutamate Decarboxylase Dopaminergic Feeding Behavior Rats Brain region nervous system chemistry Caudate Nucleus Neuroscience Acetylcholine medicine.drug |
| Zdroj: | Science. 200:1175-1177 |
| ISSN: | 1095-9203 0036-8075 |
| DOI: | 10.1126/science.653362 |
| Popis: | Intracaudate injections of kainic acid destroy striatal neurons containing acetylcholine and gamma-aminobutyric acid but leave dopaminergic nerve terminals in this brain region intact. Rats injected with the drug are aphagic and adipsic, and have other behavioral abnormalities strikingly similar to those seen in animals with lesions in the dopaminergic nigrostriatal bundle. |
| Databáze: | OpenAIRE |
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