Autoimmune polyendocrine syndrome type I and brain calcinosis
Autor: | David Groshar, Adam Steinmetz, Ruth Djaldetti, Alon Abraham, Ilan Ziv |
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Rok vydání: | 2010 |
Předmět: |
Adult
Male Pathology medicine.medical_specialty Brain calcifications Young Adult Fluorodeoxyglucose F18 Calcinosis medicine Humans Polyendocrinopathies Autoimmune Family Health Brain Diseases business.industry Parkinsonism Middle Aged medicine.disease Neurology Hypoparathyroidism Positron-Emission Tomography Autoimmune polyendocrine syndrome Female Neurology (clinical) Geriatrics and Gerontology business Calcification |
Zdroj: | Parkinsonism & Related Disorders. 16:101-104 |
ISSN: | 1353-8020 |
DOI: | 10.1016/j.parkreldis.2009.07.014 |
Popis: | Autoimmune polyendocrine syndrome (APS) is a rare disorder. One of the possible associated endocrinopathies in APS is hypoparathyroidism. We describe brain calcifications secondary to hypoparathyroidism in family members with APS and compare clinical manifestations, the extent of brain calcifications on CT scans and the result of PET–FDG scans. We found extensive brain calcifications and striatal hypometabolism in PET–FDG scan in the only symptomatic member of the family, which supports the assumption that extensive brain calcification and the presence of hypometabolism in PET–FDG scan are likely to be found in symptomatic patients with brain calcifications. |
Databáze: | OpenAIRE |
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