Nano zinc supplementation in goat ( Capra hircus ) ration improves immunity, serum zinc profile and IGF‐1 hormones without affecting thyroid hormones

Autor: Partha Sarathi Swain, S. Selvaraju, D.T. Pal, Sukanta Mondal, D. Rajendran, P. Krishnamoorthy, Somu Bala Nageswara Rao
Rok vydání: 2021
Předmět:
Zdroj: Journal of Animal Physiology and Animal Nutrition. 105:621-629
ISSN: 1439-0396
0931-2439
DOI: 10.1111/jpn.13500
Popis: The trial was aimed at evaluating probable superiority, if any of nano zinc (NZn) over inorganic zinc (Zn) on immunity, serum minerals and T3 , T4 , and IGF-1 hormone profiles in goats. NZn was synthesized by using 0.45 M aqueous solution of Zn nitrate and 0.9 M aqueous solution of sodium hydroxide (average particle size 74 nm). Twenty-four male goats were grouped into four groups as per their body weight and were supplemented with either a basal diet with concentrate and straw at 50:50 ratio (Negative control, NC) alone or supplemented with 50 mg/kg Zn (Control) from inorganic Zn source, that is ZnO (IZn-50), 50 mg/kg Zn from NZn (NZn-50) or 25 mg/kg Zn from NZn (NZn-25). No change was observed in thyroid hormone status on zero and 90th day of experimental feeding, but NZn supplementation improved (p CD 4 + (cluster of differentiation in %) was more (p CD 8 + count than NC and similar (p > 0.05) to IZn-50 and NZn-25 groups without affecting (p > 0.05) the ratio of CD 4 + , CD 8 + among the treatment groups. Thus, NZn supplementation at 25 mg/kg had similar immunity and serum T3 , T4 and IGF-1 profiles compared with IZn at 50 mg/kg dose.
Databáze: OpenAIRE