Oseltamivir-Resistant Influenza A(H1N1)pdm09 Viruses, United States, 2013–14

Autor: Margaret, Okomo-Adhiambo, Alicia M, Fry, Su, Su, Ha T, Nguyen, Anwar Abd, Elal, Elizabeth, Negron, Julie, Hand, Rebecca J, Garten, John, Barnes, Xu, Xiyan, Julie M, Villanueva, Larisa V, Gubareva, Reginald, McClinton
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Male
Epidemiology
viruses
zanamivir
lcsh:Medicine
neuraminidase
medicine.disease_cause
influenza virus
chemistry.chemical_compound
Influenza A Virus
H1N1 Subtype
Prevalence
Oseltamivir resistant
H275Y mutation
Phylogeny
biology
Neuraminidase inhibitor
Oseltamivir-Resistant Influenza A(H1N1)pdm09 Viruses
United States
2013–14
neuraminidase inhibition
Dispatch
virus diseases
Middle Aged
Infectious Diseases
pyrosequencing
Human mortality from H5N1
Female
influenza
Microbiology (medical)
Adult
Oseltamivir
Adolescent
medicine.drug_class
oseltamivir
influenza A(H1N1)pdm09 viruses
H5N1 genetic structure
Antiviral Agents
lcsh:Infectious and parasitic diseases
resistance
Viral Proteins
Young Adult
Drug Resistance
Viral
Influenza
Human
medicine
Humans
lcsh:RC109-216
lcsh:R
Influenza a
Virology
Influenza A virus subtype H5N1
United States
respiratory tract diseases
chemistry
biology.protein
Neuraminidase
Zdroj: Emerging Infectious Diseases, Vol 21, Iss 1, Pp 136-141 (2015)
Emerging Infectious Diseases
ISSN: 1080-6059
1080-6040
Popis: We report characteristics of oseltamivir-resistant influenza A(H1N1)pdm09 viruses and patients infected with these viruses in the United States. During 2013–14, fifty-nine (1.2%) of 4,968 analyzed US influenza A(H1N1)pdm09 viruses had the H275Y oseltamivir resistance–conferring neuraminidase substitution. Our results emphasize the need for local surveillance for neuraminidase inhibitor susceptibility among circulating influenza viruses.
Databáze: OpenAIRE
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