No Disadvantage to Insulin Pump Off vs Pump On During Intermittent High-Intensity Exercise in Adults With Type 1 Diabetes
| Autor: | Veronica K. Jamnik, Loren Yavelberg, Michael C. Riddell, Dessi P. Zaharieva, Ali Cinar |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Blood Glucose Male Insulin pump medicine.medical_specialty Basal rate Endocrinology Diabetes and Metabolism medicine.medical_treatment 030209 endocrinology & metabolism High-Intensity Interval Training Hypoglycemia Young Adult 03 medical and health sciences Insulin Infusion Systems 0302 clinical medicine Endocrinology Internal medicine Internal Medicine medicine Humans Hypoglycemic Agents Insulin Aerobic exercise 030212 general & internal medicine Exercise Type 1 diabetes Cross-Over Studies business.industry Blood Glucose Self-Monitoring High intensity General Medicine medicine.disease Diabetes Mellitus Type 1 Increased risk Cardiology Female business |
| Zdroj: | Canadian Journal of Diabetes. 44:162-168 |
| ISSN: | 1499-2671 |
| DOI: | 10.1016/j.jcjd.2019.05.015 |
| Popis: | Evidence suggests that patients with type 1 diabetes (T1D) performing aerobic exercise with their insulin pump connected (pump on) vs pump disconnected (pump off) have an increased risk of hypoglycemia. It has not been examined whether this risk remains during high-intensity exercise. This study compared the effects of pump on (50% basal insulin at exercise onset) vs pump off (0% basal insulin at exercise onset) on glucose concentrations during intermittent high-intensity exercise in adults with T1D and on patients' own perspective of their glycemia.Twelve adults with T1D using insulin pump therapy completed two 40-min intermittent high-intensity exercise bouts. Insulin adjustments included: 1) pump set to 50% of usual basal rate (pump on) or 2) pump suspended (pump off) during exercise, in random order. Blood glucose was recorded every 10 min during exercise and, after providing subjects with an initial reference glucose value before exercise, participants were asked to estimate their glucose during exercise.Glucose levels were higher in pump off (8.1±1.3 mmol/L) vs pump on (7.4±2.1 mmol/L) at exercise start (p0.05), but were similar by the end of exercise (p=0.9). During exercise, hypoglycemia incidence did not differ between conditions (1 of 12 for both). However, the percentage of time in hypoglycemia at 12 h after exercise was 5±8% vs 1±2% for pump on vs pump off, respectively (p=0.3). Participants were better able to estimate their own glucose during pump on vs pump off (rPump on vs pump off at exercise onset showed no significant differences in blood glucose concentrations during 40 min of intermittent high-intensity exercise. |
| Databáze: | OpenAIRE |
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