Therapeutic effects of iontophoresis with gold nanoparticles in the repair of traumatic muscle injury

Autor:	Jeandro Paes Fonseca, Natalia dos Santos Tramontin, Daniela Pacheco Dos Santo Haupenthal, Marcos Marques da Silva Paula, Franciani Rodrigues da Rocha, Maria Eduarda Anastácio Borges Corrêa, Ricardo A. Pinho, Renata Tiscoski Nesi, Alexandre Pastoris Muller, Paulo Cesar Lock Silveira, Rubya Pereira Zaccaron
Rok vydání:	2019
Předmět:	Male Pharmaceutical Science Metal Nanoparticles Inflammation 02 engineering and technology Pharmacology medicine.disease_cause 03 medical and health sciences 0302 clinical medicine medicine Animals Rats Wistar Muscle Skeletal Iontophoresis business.industry Therapeutic effect 021001 nanoscience & nanotechnology Muscle injury Rats Disease Models Animal Oxidative Stress Colloidal gold 030220 oncology & carcinogenesis Gold medicine.symptom 0210 nano-technology business Oxidative stress
Zdroj:	Journal of drug targeting. 28(3)
ISSN:	1029-2330
Popis:	Studies have shown the benefits of gold nanoparticles (GNPs) in muscle and epithelial injury models. In physiotherapy, the use of the microcurrent apparatus is associated with certain drugs (Iontophoresis) to increase the topical penetration and to associate the effects of both therapies. Therefore, the objective of this study was to investigate the effects of iontophoresis along with GNPs in the skeletal muscle of rats exposed to a traumatic muscle injury. We utilised 50 Wistar rats randomly divided in to five experimental groups (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a26bc9fddf4f2bd8d38c71e6db4374 https://pubmed.ncbi.nlm.nih.gov/31379221 Zobrazit plný text záznamu