Effect of the compression ratio on properties of lung surfactant (bovine lipid extract surfactant) films

Autor: J.Y. Lu, K. Philips, A.W. Neumann, P. Chen, J. Distefano
Rok vydání: 1999
Předmět:
Zdroj: Respiration physiology. 115(1)
ISSN: 0034-5687
Popis: Using axisymmetric drop shape analysis (ADSA) and a captive bubble technique, the properties of lung surfactant (BLES) films under different compression ratios (i.e. the ratio of maximum to minimum surface area of the bubble) were investigated. In particular, the effect of the compression ratio of the films on the shape of the volume–area–surface tension–time (VAST) graphs and on the shape of the surface tension–relative area ( γ – A ) graphs was examined at the air–liquid interface. Under relatively low compression ratios of the films, the VAST and γ – A graphs indicate that the cycling is reversible (i.e. the γ – A graphs are identical for expansion and compression). When the compression ratio of the films increases, failure tends to occur when the surface film can not support the increasing surface pressure, causing a hysteresis loop in the γ – A graph. It was also found that low surface tension (i.e. below 5 mJ/m 2 ) at the interface could be attained with a 30% compression ratio and collapse of the films always occurs near or below 1 mJ/m 2 .
Databáze: OpenAIRE